PHENYLARTHRITE Injection is designed for the rapid and effective control of inflammatory processes, fever, and pain in animals. It combines two powerful ingredients: phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID), and dexamethasone, a synthetic glucocorticoid with significant anti-inflammatory and anti-allergic properties.

Composition

Each 100 mL of PHENYLARTHRITE contains:

• Phenylbutazone: 18.00 g
• Dexamethasone Sodium Phosphate: 35.00 mg
• Vehicle q.s.p.: 100.00 mL

Indications

PHENYLARTHRITE is indicated for:

• Arthritis
• Tendinitis
• Articular and muscular rheumatism
• Congestive processes
• Hyperthermia and heat stroke
• Inflammatory complications from traumatic or microbial conditions

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Dosage Guidelines

Dosage varies by species:

• Adult Horses:
  3 to 4 mL per 100 kg body weight by slow intravenous injection every 24 to 48 hours.
• Foals:
  1 to 2 mL per 50 kg body weight by slow intravenous injection every 24 to 48 hours.
• Dogs:
  1 mL per 15 kg body weight by slow intravenous injection daily (maximum daily dose: 800 mg).

Treatment Duration

• Horses:
  Initial high doses for the first 48 hours, gradually reducing to a maintenance level. Treatment duration averages 7 days, ranging from 3 to 14 days.
• Dogs:
  Recommended treatment duration is 3 days.

Administration Method

• Route:
  Administer slowly via intravenous (preferred for horses) or deep intramuscular injection.
• Aseptic Technique:
  Ensure all injections are performed under strict aseptic conditions.

Precautions

• Administer intravenous injections very slowly.
• Deep intramuscular injections should be performed adequately into the muscle mass.
• Determine treatment duration and repetition under veterinary guidance.
• Monitor for infections in cases of concurrent acute or chronic bacterial infections.

Contraindications:

• Heart, liver, or kidney failure
• Advanced pregnancy (last third of gestation)
• Diabetes